Detalhe da pesquisa
1.
Siglecs as potential targets of therapy in human mast cell- and/or eosinophil-associated diseases.
Semin Immunol
; 69: 101799, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37413923
2.
Mast cell silencing: A novel therapeutic approach for urticaria and other mast cell-mediated diseases.
Allergy
; 79(1): 37-51, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605867
3.
Regulation of mast cells by overlapping but distinct protein interactions of Siglec-6 and Siglec-8.
Allergy
; 79(3): 629-642, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38186079
4.
Safety and efficacy of lirentelimab in patients with refractory indolent systemic mastocytosis: a first-in-human clinical trial.
Br J Dermatol
; 189(5): 511-519, 2023 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37290787
5.
Lirentelimab for severe and chronic forms of allergic conjunctivitis.
J Allergy Clin Immunol
; 150(3): 631-639, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390403
6.
Mast Cell and Eosinophil Counts in Gastric and Duodenal Biopsy Specimens From Patients With and Without Eosinophilic Gastroenteritis.
Clin Gastroenterol Hepatol
; 19(10): 2102-2111, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32801015
7.
An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells.
Clin Exp Allergy
; 50(8): 904-914, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542913
8.
Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies.
J Allergy Clin Immunol
; 143(6): 2227-2237.e10, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30543818
9.
High Discovery Rate of Duodenal and Gastric Eosinophilia in Patients With Unexplained Moderate-Severe Abdominal Symptoms: A Prospective US Multisite Study.
Gastroenterology
; 164(4): 680-683.e2, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36574864
10.
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Int Arch Allergy Immunol
; 180(2): 91-102, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31401630
11.
Mast cell activation is associated with post-acute COVID-19 syndrome.
Allergy
; 77(4): 1288-1291, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34820848
12.
CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3' end processing.
Nucleic Acids Res
; 42(13): 8330-42, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24957598
13.
Detecting Changes in Mast Cell Numbers Versus Activation in Human Disease: A Roadblock for Current Biomarkers?
J Allergy Clin Immunol Pract
; 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467332
14.
Siglecs in allergy and asthma.
Mol Aspects Med
; 90: 101104, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35835621
15.
The Number of MRGPRX2-Expressing Cells Is Increased in Skin Lesions of Patients With Indolent Systemic Mastocytosis, But Is Not Linked to Symptom Severity.
Front Immunol
; 13: 930945, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35958589
16.
The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation.
Front Immunol
; 13: 833728, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35154156
17.
Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells.
Commun Biol
; 5(1): 1226, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36369358
18.
Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells.
Cells
; 11(7)2022 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35406705
19.
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody.
Front Immunol
; 12: 650331, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33777047
20.
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation.
Mucosal Immunol
; 14(2): 366-376, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814824